How to use the Bayley’s Scale of Infant and Toddler Development, Chelo Del Rosario,Marie Slevin, Eleanor J MolloyJean QuigleyElizabeth Nixon

The Bayley Scales of Infant and Toddler Development is a gold standard series of behavioural assessments used by clinicians and researchers to assess the developmental functioning of young children. This paper aims to discuss how to pick an appropriate developmental assessment and  outlines indications for the use of the Bayley-III in comparison with other commonly used tools for the assessment of development in children. It discusses the value of the Bayley-III and some of its limitations.

Click here to read more about the PANDA project which is one of the five PhD research projects in the NEPTuNE programme.

A machine-learning algorithm for neonatal seizure recognition: a multicentre, randomised, controlled trial, Andreea M Pavel, Janet M Rennie, Linda S de Vries, Mats Blennow, Adrienne Foran, Divyen K Shah, Ronit M Pressler, Olga Kapellou, Eugene M Dempsey, Sean R Mathieson, Elena Pavlidis, Alexander C van Huffelen, Vicki Livingstone, Mona C Toet, Lauren C Weeke, Mikael Finder, Subhabrata Mitra, Deirdre M Murray, William P Marnane, Geraldine B Boylan

Despite the availability of continuous conventional electroencephalography (cEEG), accurate diagnosis of neonatal seizures is challenging in clinical practice. Algorithms for decision support in the recognition of neonatal seizures could improve detection. We aimed to assess the diagnostic accuracy of an automated seizure detection algorithm called Algorithm for Neonatal Seizure Recognition (ANSeR).

Click to read commentary on this paper and further information about  Andreea’s SERENdiPITY project can also be found on our site. The project is part of the NEPTuNE programme.

Diffusion Weighted Imaging in Neonatal Encephalopathy: A Systematic Review, Megan Dibble, Mary I. O’Dea, Tim Hurley, Angela T. Byrne , Gabrielle Colleran, Eleanor J. Molloy and Arun L. W. Bokde

Diffusion tensor imaging (DTI) during the first few days of life can be used to assess brain injury in neonates with neonatal encephalopathy for outcome prediction. The goal of this review was to identify specific white matter tracts of interest that can be quantified by DTI as being altered in neonates with this condition, and to investigate its potential prognostic ability.

Click here to read more about the NEON project which is one of the five PhD research projects in the NEPTuNE programme.

Severe neurological impairment: a review of the definition. Developmental Medicine & Child Neurology, Allen J, Molloy E, McDonald D.

SNI (Severe Neurological Impairment) is a term used widely in medical literature and this review demonstrates that there is wide variation in how it is applied. With the introduction of Core Outcome Sets and Reporting Guidelines, there is an emphasis on having a uniform definition of a patient cohort. An improved definition will provide better accuracy in assessing prevalence, conducting research, planning medical resources and evaluating outcomes.

Click here to read more about the SERENITY programme.

Coagulation Profiles Are Associated with Early Clinical Outcomes in Neonatal Encephalopathy.  Sweetman D, Kelly LA, Zareen Z, Nolan B, Murphy J, Boylan G, Donoghue V, Molloy EJ.

Click here to read more about the NIMBUS project.

Parental involvement in a multidisciplinary PhD programme in neonatal brain injuryEleanor J. MolloyMandy Daly, Paul Ryan, Paul CorcoranArun Bokde, Jean QuigleyElizabeth Nixon, Sabina BrennanDeclan DevaneMark Watson, Beth Corcoran, Deirdre Murray, Fiona O’Farrell, Sharon Keogh, Elaine Ni Bhraonain, Geraldine Boylan,

Parental and patient and public involvement (PPI) involvement is a core element of the Neonatal Brain Consortium Ireland Ireland (NBCI) since its inception. PPI  representatives were critical to the development of the Consortium and the animations for parent information as well as the NEPTUNE Neonatal Encephalopathy PhD programme in which they are core members involved in PhD supervision, publications, study days and educational outreach. Key outputs have also included national clinical guidelines and parent information.

Click here to read more about the NEPTuNE programme.


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