Identify characteristic features or ‘biomarkers’ of encephalopathy in newborn infants using EEG

Supervisors

  • Professor Geraldine Boylan (UCC) and Professor Deirdre Murray (UCC)

Description

The aim of this project is to use detailed analysis of electroencephalography (EEG) in newborn infants to identify characteristic features or ‘biomarkers’ of encephalopathy (all causes) and to identify features that are most predictive of poor neurodevelopmental outcome.

The commonest cause of Neonatal Encephalopathy (NE) is hypoxia-ischaemia (HI) but other disorders such as sepsis, genetic and metabolic disorders may closely mimic the clinical features. It is sometimes difficult to distinguish the cause of encephalopathy in the first few days after birth and to predict longer term outcome. This project aims to characterise the standard EEG features seen in all cause NE using EEGs from a large database of studies available at INFANT.  This project will also identify features that are most predictive of poor neurodevelopmental outcome.

NEPTuNE Scholar: Andreea Pavel

Andreea Pavel


biography

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